Catalogue supplier of over 140,000 heterocyclic building blocks and complex scaffolds for medicinal chemistry.

Activate Scientific GmbH

Prien, Germany · Littleport (Ely), United KingdomNew on Amplifa

2010Founding of Activate Scientific UK Limited (Companies House)

140.000+Compounds in the catalogue

mg–kgScale of custom synthesis

95 %Catalogue products in stock

About Activate Scientific

Activate Scientific is a European catalogue supplier of multifunctional heterocyclic building blocks and complex scaffolds, headquartered in Prien (Bavaria) with a second location in Littleport (UK). The catalogue range comprises more than 140,000 compounds, including heterocycles, boronic acids, fluorinated compounds, spiro compounds, cycloalkyls, amino acids, PEG linkers, alkynes and azides for pharmaceutical research and synthetic chemistry. In addition, the company offers custom synthesis from milligram to kilogram quantities, including process development and scale-up through to pilot production, with a specialization in heterocyclic chemistry, fluorine chemistry, boronic acid derivatives and chiral synthesis. Every batch is analytically tested (NMR, HPLC, LC-MS) and documented with a CoA; 95 % of catalogue products are in stock and are delivered worldwide within five working days. Customers include pharmaceutical companies, biotech firms and academic research institutions.

Site: Prien
Processes: Custom synthesis (mg to kg), Scale-up / process development through to pilot production, Chiral synthesis, Quality control / analytics (NMR, HPLC, LC-MS), CoA/MSDS documentation, Structure search (Marvin JS), Worldwide shipping including dangerous goods and customs documentation, SAP Ariba as procurement channel
Materials: N-Heterocycles, Boronic Acids, Spiro Compounds and Cycloalkyls, Fluorinated Compounds, Chiral Compounds
Certificates: Analytical QC (NMR, HPLC, LC-MS), CoA for every delivery, ISO 9001 (verified)
Industries: Pharmaceutical industry, Biotechnology, Academic research, Medicinal chemistry / Drug Discovery

01
Catalogue and synthesis planning based on trends in medicinal chemistry
02
Chemical synthesis / custom synthesis (mg–kg)
03
Scale-up and process development through to pilot production
04
Quality control and analytics (NMR, HPLC, LC-MS)
05
Documentation (CoA, MSDS)
06
Warehousing in Germany and the UK
07
Worldwide shipping including dangerous goods and customs documentation

Compounds and Synthesis Services

N-Heterocyclen

N-Heterocycles

Core category of the catalogue for medicinal chemistry and drug discovery.

Boronsäuren

Boronic Acids

Frequently requested building blocks for cross-coupling reactions.

Spiro

Spiro Compounds and Cycloalkyls

Complex scaffolds for increasing chemical diversity.

Fluor

Fluorinated Compounds

Specialty area within the custom synthesis services.

Chiral

Chiral Compounds

Enantiomeric excess is determined by optical rotation or chiral HPLC.

Locations

Prien

Headquarters, office and warehouse (EU shipping)

Materials: Building blocks, custom synthesis

Littleport (Ely)

UK office and warehouse

Materials: Building blocks

Building Blocks

**5-Bromo-2-iodo-1H-indole 97%**Catalogue compound · Drug Discovery

**1-Boc-3-(3-ethoxy-3-oxo-propyl)piperidine 97%**Catalogue compound · Medicinal Chemistry

**1-Cyclopropylpyrrolidin-3-amine diHCl 97%**Catalogue compound · Drug Discovery

**4-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 97%**Catalogue compound · Medicinal Chemistry

**N-(4-Bromo-5-fluoro-1H-indol-7-yl)-2,2,2-trifluoro-acetamide 97%**Catalogue compound · Drug Discovery

**2-Oxo-1,2,5,6,7,8-hexahydroquinoline-4-carboxylic Acid 95%**Catalogue compound · Medicinal Chemistry

**2-Boc-2-azaspiro[3.5]nonan-5-one 97%**Catalogue compound · Drug Discovery

**cis-1-Methyl-3a,4,5,6,7,7a-hexahydro-3H-imidazo[4,5-c]pyridin-2-one HCl 97%**Catalogue compound · Medicinal Chemistry

**trans-4-Methoxytetrahydrofuran-3-ol 95%**Catalogue compound · Drug Discovery

**[1,3]Dioxolo[4,5-b]pyridine 95%**Catalogue compound · Medicinal Chemistry

Inside the production

Industries

Pharmaceutical industryBiotechnologyAcademic researchMedicinal chemistry / Drug Discovery

Additional services

Custom synthesis (mg to kg)Scale-up / process development through to pilot productionChiral synthesisQuality control / analytics (NMR, HPLC, LC-MS)CoA/MSDS documentationStructure search (Marvin JS)Worldwide shipping including dangerous goods and customs documentationSAP Ariba as procurement channel

Reference customers

Large pharmaceutical companies (unspecified)Biotechnology firmsAcademic research institutionsTU Dresden (named as a source)

Quality and Analytics

Every batch is tested by ¹H-/¹³C-NMR, HPLC and LC-MS and delivered with a Certificate of Analysis (CoA); standard purity is 95 %, with many products at >98 % or >99 %. The enantiomeric excess of chiral compounds is determined by optical rotation or chiral HPLC.

Evidence	Prien	Littleport (Ely)
Analytical QC (NMR, HPLC, LC-MS)
CoA for every delivery
ISO 9001 (verified)

History

2010
Founding of Activate Scientific UK Limited on 29 April 2010 (Companies House No. 07238574).
More than 20 years of experience as a supplier of building blocks for medicinal chemistry (self-reported).