Platform for safety assessment with In-silico and In-vitro methods (NAMs) for the development of safer products.
Edelweiss Connect GmbH
Basel (Technology Park Basel)New on Amplifa
About SaferWorldbyDesign
SaferWorldbyDesign is the brand name of Edelweiss Connect GmbH, a safety assessment solution platform headquartered in Basel Technology Park. The company supports the development and testing of safe products with New Approach Methodologies (NAMs) in toxicology and next-generation risk assessment. It integrates In-silico and In-vitro procedures into standardized and Premium-Integrated Approaches to Testing and Assessment (IATAs), including for ingredient screening, product design, and regulatory dossiers. Solutions include in-vitro tests for compounds and formulations, the SaferSkin™ platform for skin sensitization, HepaRG™ cell systems for hepatotoxicity, SaferNeuron (neurotoxicity), and SaferKidney (nephrotoxicity), as well as data integration with EdelweissData™, text mining with Taxila™, and Machine Learning/AI data analysis. Customers come from the cosmetics, pharmaceutical, medical device, chemical, and food industries. The company follows the 3Rs principles (Replacement, Reduction, Refinement) to reduce and replace animal testing and also offers consulting, pre-clinical safety testing, and training.
- Site
- Basel
- Processes
- In-vitro tests/assays for cosmetics, pharma, medical devices, chemical, and food industries, In-silico Testing (NAMs, New Approach Methodologies), IATA (Integrated Approaches to Testing and Assessment) for skin sensitization (SaferSkin™), Hepatotoxicity testing (HepaRG™ cell lines, in-vitro ADME, inhibition assays,, Nephrotoxicity assessment and mechanistic toxicology (Cellular Impedance, HCI, Lactate,, Neurotoxicity assessment of compounds (SaferNeuron), Skin-Discs and product testing for skin tolerance and irritation, Formulation assessment / Pre-clinical safety testing
- Materials
- New Approach Methodologies (In-silico/In-vitro), Integrated Approaches to Testing and Assessment, SaferSkin™ Platform, HepaRG™ Cell System, EdelweissData™ Data Platform, Taxila™ Text-Mining
- Industries
- Cosmetics, Pharma, Medical Devices, Chemical, Food, Textile
- 01
Consulting and Problem Definition
- 02
In-silico Testing
- 03
In-vitro Testing (IATA)
- 04
Data Integration and Analysis
- 05
Report and Recommendation
Methods and Platforms
New Approach Methodologies (In-silico/In-vitro)
Tier-free methods for toxicology assessment in tiered testing strategies.
Integrated Approaches to Testing and Assessment
Integration of in-silico and in-vitro evidence for safety assessments and regulatory dossiers.
SaferSkin™ Platform
OECD-based evaluation of skin sensitization including DPRA, KeratinoSens, and h-CLAT assays.
HepaRG™ Cell System
Hepatic cell system for in-vitro ADME, metabolite, cholestasis, and virology (HBV/HCV).
EdelweissData™ Data Platform
Harmonized data integration from various formats, sources, and laboratories including predictive modeling.
Taxila™ Text-Mining
Text mining and aggregation for actionable insights.
Locations
Basel
CHOffice / Technology Park Basel
- Materials
- In-vitro/In-silico services, trainings
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| In-vitro tests/assays for cosmetics, pharma, medical devices, chemical, and food industriesTesting | – | – | – | – | – |
| In-silico Testing (NAMs, New Approach Methodologies)Testing | – | – | – | – | – |
| IATA (Integrated Approaches to Testing and Assessment) for skin sensitization (SaferSkin™)Testing | – | – | – | – | Chemical, Formulations |
| Hepatotoxicity testing (HepaRG™ cell lines, in-vitro ADME, inhibition assays,Testing | – | – | – | – | – |
| Nephrotoxicity assessment and mechanistic toxicology (Cellular Impedance, HCI, Lactate,Testing | – | – | – | – | – |
| Neurotoxicity assessment of compounds (SaferNeuron)Testing | – | – | – | – | – |
| Skin-Discs and product testing for skin tolerance and irritationTesting | – | – | – | – | – |
| Formulation assessment / Pre-clinical safety testingTesting | – | – | – | – | – |
| Toxicological and regulatory consulting, Regulatory Affairs, Regulatory DossiersEngineering | – | – | – | – | – |
| Data Integration and Predictive Modelling (EdelweissData™), Text Mining (Taxila™), MachineEngineering | – | – | – | – | – |
| Training: Skin Safety Assessment (DPRA, KeratinoSens, h-CLAT Assays)Testing | – | – | – | – | – |
Additional services